Panama offers an incredible mix of pristine beaches, lush rainforests, and vibrant cities, making it one of Central America’s most diverse destinations. This narrow isthmus connecting two continents packs an impressive array of experiences into a relatively small area. From the engineering marvel of the Panama Canal to the paradise-like San Blas Islands, Panama rewards travelers with unforgettable adventures and stunning landscapes.
Essential Panama Travel Resources
Before exploring the best places to visit in Panama, make sure you’re prepared with these travel essentials:
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Panama’s stunning capital city showcases the country’s blend of modern architecture and natural beauty
1. Panama City, Central Panama
Panama City stands as Central America’s most cosmopolitan capital, offering a fascinating blend of historic charm and modern sophistication. This vibrant metropolis serves as the perfect introduction to the country, with its impressive skyline reflecting off the Pacific Ocean at the canal’s entrance.
The colorful colonial architecture of Casco Viejo offers a stark contrast to the modern downtown
Why Visit
As a tale of three cities in one, Panama City offers the ultramodern banking district downtown, the atmospheric colonial-era Casco Viejo, and the archaeological site of Panamá Viejo. This diversity makes it possible to experience centuries of history alongside cutting-edge urban development.
Highlights
- Explore the UNESCO-listed Casco Viejo with its cobblestone streets, colonial buildings, and trendy rooftop bars
- Visit the ruins of Panamá Viejo, the original city founded in 1519 and later destroyed by pirates
- Hike through the rainforest trails of Metropolitan Natural Park, an urban jungle teeming with wildlife
- Stroll or cycle along the scenic Amador Causeway with views of ships entering the Panama Canal
- Experience the city’s vibrant culinary scene, from seafood markets to upscale fusion restaurants
Pro Tip: Panama City can get extremely hot and humid. Stay connected with weather updates and navigation apps by securing a Panama eSIM before your trip, which will help you navigate between attractions and call taxis when needed.
2. San Blas Islands (Guna Yala), Caribbean Coast
The San Blas archipelago consists of over 365 islands (one for each day of the year) off Panama’s Caribbean coast. This semi-autonomous region is home to the indigenous Guna people who maintain their traditional way of life while sharing their paradise with visitors.
The pristine beaches and crystal-clear waters of San Blas offer a true Caribbean paradise
Why Visit
San Blas offers the quintessential Caribbean experience with pristine beaches, crystal-clear waters, and a fascinating indigenous culture. The islands remain largely undeveloped, providing an authentic escape from modern life and a glimpse into traditional Guna culture.
Highlights
- Island-hop between dozens of picture-perfect tropical islands with powdery white sand
- Snorkel in clear waters teeming with colorful fish and coral reefs
- Stay in rustic over-water cabins or beachfront huts for an authentic experience
- Purchase handcrafted molas, the colorful textile art created by Guna women
- Learn about Guna culture and traditions directly from the indigenous communities
Pro Tip: There’s virtually no internet connectivity on most San Blas islands. Download offline maps and information before visiting, and consider booking your San Blas tour in advance as accommodations are limited and fill up quickly during high season.
3. Bocas del Toro, Caribbean Coast
The Bocas del Toro archipelago on Panama’s northern Caribbean coast has evolved into a premier destination for travelers seeking a laid-back tropical vibe with plenty of activities. This collection of islands offers something for everyone, from backpackers to luxury travelers.
Colorful over-water accommodations are part of Bocas del Toro’s unique charm
Why Visit
Bocas del Toro blends Caribbean culture, pristine nature, and a vibrant social scene. The archipelago’s biodiversity both above and below water makes it ideal for nature lovers, while its relaxed atmosphere and range of accommodations appeal to all types of travelers.
Highlights
- Explore the colorful Caribbean-style architecture of Bocas Town on Isla Colón
- Visit Red Frog Beach on Isla Bastimentos, known for its beautiful shores and tiny red frogs
- Snorkel or dive at Coral Cay, home to vibrant coral gardens and marine life
- Take a boat tour to Dolphin Bay to spot bottlenose dolphins in their natural habitat
- Experience the archipelago’s famous nightlife with beachfront bars and restaurants
Pro Tip: Bocas del Toro has better connectivity than San Blas, but service can still be spotty on some islands. A reliable eSIM will help you stay connected between islands and coordinate boat taxis, which are the main form of transportation in the archipelago.
4. Boquete, Chiriquí Province
Nestled in the highlands of western Panama, Boquete offers a refreshing contrast to the country’s tropical coastlines. This charming mountain town sits in the shadow of Volcán Barú and is renowned for its spring-like climate, coffee plantations, and outdoor adventures.
Boquete’s world-famous coffee plantations thrive in the rich volcanic soil and ideal climate
Why Visit
After the heat of Panama’s lowlands, Boquete’s cool mountain air is a welcome relief. The town combines natural beauty with adventure activities and culinary experiences, making it popular with both adrenaline seekers and those looking to relax in scenic surroundings.
Highlights
- Hike to the summit of Volcán Barú, Panama’s highest peak, for sunrise views of both the Pacific and Caribbean
- Tour coffee plantations to learn about and taste some of the world’s most expensive coffee, including Geisha varieties
- Spot the resplendent quetzal and other exotic birds in the cloud forests
- Go whitewater rafting on the Chiriquí Viejo River with rapids for all skill levels
- Relax in natural hot springs surrounded by tropical gardens
Pro Tip: Hiking trails around Boquete can be challenging to navigate independently. Use your Panama eSIM to access trail maps and weather forecasts, which are crucial as conditions can change rapidly in the mountains. For the best hotel rates in this popular destination, check travel deals well in advance.
5. Panama Canal, Central Panama
No visit to Panama would be complete without experiencing its most famous landmark. The Panama Canal stands as one of the world’s greatest engineering achievements, connecting the Atlantic and Pacific Oceans and revolutionizing global maritime trade since its opening in 1914.
Watching massive ships navigate the locks is a fascinating experience that showcases human ingenuity
Why Visit
The Panama Canal offers a unique opportunity to witness one of humanity’s most impressive feats of engineering in action. Seeing massive ships being raised and lowered through the lock system provides perspective on global commerce and Panama’s strategic importance.
Highlights
- Visit the Miraflores Visitor Center with its museum, film presentation, and observation decks
- Watch ships transit through the locks, a process that takes about 8-10 minutes per chamber
- Learn about the canal’s fascinating history, from the failed French attempt to the American completion
- Take a partial transit tour to experience the canal from the water
- Visit the newer Agua Clara Visitor Center on the Atlantic side to see the expanded locks
Pro Tip: Check the Panama Canal Authority website for ship transit schedules to time your visit when large vessels will be passing through. The best viewing times are typically between 9 AM and 11 AM or 3 PM and 5 PM. Book a canal transit tour in advance as they often sell out during high season.
6. El Valle de Antón, Coclé Province
El Valle de Antón is a picturesque town uniquely situated in the crater of an extinct volcano. Located just two hours from Panama City, this lush mountain retreat offers a cool climate and natural attractions that make it perfect for a refreshing escape.
El Chorro Macho waterfall is one of El Valle’s most popular natural attractions
Why Visit
El Valle combines natural beauty with cultural attractions in a unique volcanic setting. The town’s elevation provides a pleasant climate year-round, making it ideal for outdoor activities while its Sunday market showcases local crafts and produce.
Highlights
- Hike to the La India Dormida (Sleeping Indian Girl) mountain formation for panoramic views
- Visit El Chorro Macho waterfall and cross its hanging bridge through the canopy
- Explore the local market for handicrafts, plants, and fresh produce
- Relax in natural hot springs and mud baths with therapeutic minerals
- Visit the El Níspero Zoo and Botanical Garden, home to the endangered Panamanian golden frog
Pro Tip: El Valle is busiest on weekends when city dwellers escape the heat. Visit mid-week for a more tranquil experience and better accommodation rates. Check hotel deals that often include transportation from Panama City.
7. Coiba National Park, Veraguas Province
Often called “Panama’s Galápagos,” Coiba National Park encompasses Panama’s largest island and the surrounding marine ecosystem. This UNESCO World Heritage site remained largely untouched due to its history as a penal colony until 2004, preserving its pristine ecosystems.
Coiba’s protected waters host some of the best-preserved coral reefs in the Pacific
Why Visit
Coiba offers world-class diving and snorkeling in some of the most biodiverse waters in the Americas. The island’s isolation has preserved both its marine and terrestrial ecosystems, making it a paradise for nature enthusiasts and underwater photographers.
Highlights
- Dive or snorkel at Granito de Oro, a small island surrounded by vibrant coral gardens
- Spot marine life including whale sharks, rays, turtles, and numerous fish species
- Watch for humpback whales during their migration season (July to October)
- Explore the island’s trails to see endemic birds and howler monkeys
- Visit the abandoned prison buildings that tell the island’s dark history
Pro Tip: Coiba is only accessible by boat from Santa Catalina or Mariato on the mainland. Tours should be booked in advance, especially during high season. There’s no cell service on the island, so download any necessary information before your trip.
8. Santa Catalina, Veraguas Province
Santa Catalina has transformed from a quiet fishing village into a laid-back surf destination with rustic charm. Located on Panama’s Pacific coast, it serves as the gateway to Coiba National Park while offering its own attractions for surfers and beach lovers.
Santa Catalina is renowned for its consistent surf breaks suitable for various skill levels
Why Visit
Santa Catalina offers world-class surfing in a relaxed atmosphere far from the crowds. Its position as the jumping-off point for Coiba National Park makes it ideal for combining surf adventures with diving and snorkeling excursions.
Highlights
- Surf at Playa Santa Catalina, known for its consistent reef break suitable for experienced surfers
- Take surfing lessons at the more beginner-friendly Playa Estero
- Arrange diving or snorkeling trips to Coiba National Park
- Enjoy fresh seafood at local restaurants, often caught the same day
- Experience spectacular sunsets over the Pacific Ocean
Pro Tip: Santa Catalina has limited ATMs and spotty internet. Bring sufficient cash and download maps offline. A Panama eSIM will help you stay connected when signal is available, which is important for checking surf conditions and booking tours.
9. Portobelo, Colón Province
Once one of the most important Spanish ports in the Americas, Portobelo is now a sleepy fishing town rich in history and culture. Its strategic location on the Caribbean coast made it the transit point for Peruvian gold and silver bound for Spain, attracting pirates including the infamous Henry Morgan.
The ruins of Spanish fortifications tell the story of Portobelo’s strategic importance
Why Visit
Portobelo offers a fascinating glimpse into colonial history and Afro-Panamanian culture. The UNESCO-listed fortifications, combined with the town’s vibrant Congo culture and beautiful bay setting, create a unique destination that blends history, culture, and natural beauty.
Highlights
- Explore the ruins of Spanish fortifications including Fuerte San Jerónimo and Fuerte Santiago
- Visit the Iglesia de San Felipe to see the venerated Black Christ statue
- Learn about the Congo culture at the Congo Museum and through local art
- Enjoy diving and snorkeling in the clear Caribbean waters
- Time your visit for the Festival of the Black Christ (October 21) or Congo Festival (during Carnival)
Pro Tip: Portobelo can be visited as a day trip from Panama City, but staying overnight allows you to experience the town after day-trippers leave. Book accommodations in advance as options are limited, especially during festivals.
10. Pearl Islands (Archipiélago de las Perlas), Gulf of Panama
The Pearl Islands archipelago consists of 200 islands and islets in the Gulf of Panama, just a short flight or ferry ride from Panama City. Named for the pearls once harvested there, these islands offer pristine beaches and exclusive resorts alongside traditional fishing villages.
Contadora Island is the most developed of the Pearl Islands, offering beautiful beaches and upscale amenities
Why Visit
The Pearl Islands provide a more accessible alternative to San Blas, with better infrastructure while still offering stunning beaches and clear waters. The archipelago’s mix of developed and untouched islands allows for various experiences, from luxury resorts to secluded beaches.
Highlights
- Relax on the white-sand beaches of Contadora Island, the archipelago’s main tourist hub
- Spot humpback whales during their migration season (July to October)
- Explore the larger Isla del Rey with its traditional villages and diverse landscapes
- Enjoy world-class sport fishing for marlin, tuna, and other game fish
- Visit filming locations from several seasons of the Survivor reality show
Pro Tip: Ferry service to Contadora Island can be unreliable. Check schedules in advance and consider flying instead. Most islands have limited or no internet access, so a reliable eSIM is essential for staying connected where coverage is available.
11. Azuero Peninsula, Southern Panama
Often called Panama’s cultural heartland, the Azuero Peninsula preserves traditional Panamanian customs, folklore, and crafts. This rural region extends into the Pacific Ocean and is known for its festivals, distinctive pottery, and increasingly popular beaches.
The Azuero Peninsula is famous for its vibrant cultural traditions and festivals
Why Visit
The Azuero Peninsula offers an authentic glimpse into rural Panamanian life and traditions. Its combination of cultural experiences, artisanal crafts, and beautiful beaches makes it ideal for travelers seeking to experience Panama beyond the tourist hotspots.
Highlights
- Experience Panama’s most famous Carnival celebrations in Las Tablas (February)
- Visit Pedasí, a charming town that serves as a base for exploring nearby beaches
- Surf at Playa Venao, a horseshoe-shaped bay with consistent waves
- Watch turtle nesting at Isla Cañas (July to November)
- Shop for traditional handicrafts including painted masks, pottery, and textiles
Pro Tip: The Azuero Peninsula is large and public transportation is limited. Consider renting a car to explore the region thoroughly. During Carnival and other festivals, book accommodations months in advance as the entire region fills up quickly.
12. Chiriquí Highlands, Western Panama
Beyond Boquete, the Chiriquí Highlands offer additional mountain retreats with their own distinct character. This region near the Costa Rican border features cloud forests, coffee plantations, and some of Panama’s most dramatic landscapes.
The misty cloud forests of Chiriquí create a mystical atmosphere perfect for nature exploration
Why Visit
The Chiriquí Highlands expand on what Boquete offers with less touristic development. Towns like Volcán and Cerro Punta provide access to pristine natural areas, agricultural experiences, and outdoor adventures in a more laid-back setting.
Highlights
- Hike in La Amistad International Park, a UNESCO World Heritage site shared with Costa Rica
- Visit Cerro Punta, Panama’s agricultural center, known for its vegetable farms and flower nurseries
- Explore the cloud forests of Volcán Barú National Park from the western side
- Bird-watch in the highlands, home to over 500 bird species including the resplendent quetzal
- Tour smaller, family-run coffee farms for a more intimate experience
Pro Tip: The Chiriquí Highlands experience frequent afternoon rain, especially during the wet season (May to November). Plan outdoor activities for the morning and bring rain gear. Cell service can be spotty in remote areas, so a reliable eSIM with good coverage is essential for navigation.
13. Darién Gap, Eastern Panama
The Darién Gap represents one of the last truly wild frontiers in the Americas. This largely undeveloped region between Panama and Colombia is the only break in the Pan-American Highway and contains some of Central America’s most pristine rainforests and indigenous territories.
The pristine rainforests of Darién National Park are among the most biodiverse in Central America
Why Visit
For adventurous travelers, the Darién offers an unparalleled wilderness experience. This UNESCO World Heritage site contains extraordinary biodiversity and provides insight into the traditional lifestyles of the Emberá and Wounaan indigenous peoples.
Highlights
- Visit Darién National Park with a certified guide to explore its diverse ecosystems
- Experience indigenous culture in Emberá villages along the rivers
- Bird-watch in one of Central America’s richest avian habitats
- Photograph rare wildlife including harpy eagles, jaguars, and tapirs (if you’re lucky)
- Learn about conservation efforts in this critical biological corridor
Pro Tip: The Darién should only be visited with experienced guides and proper preparation. Some areas near the Colombian border are not safe for tourists. Arrange tours through reputable agencies in Panama City and ensure you have emergency communication options as there’s no cell service in most of the region.
14. Taboga Island, Gulf of Panama
Known as the “Island of Flowers,” Taboga lies just 12 miles from Panama City but feels worlds away. This volcanic island offers a convenient escape from the capital with its colorful village, beaches, and hiking trails.
The charming village of Taboga climbs up the hillside from the harbor
Why Visit
Taboga provides a perfect day trip or weekend getaway from Panama City. Its accessibility, combined with its laid-back atmosphere, beaches, and hiking opportunities, makes it an easy addition to any Panama itinerary.
Highlights
- Relax on the main beach with views of ships waiting to enter the Panama Canal
- Hike to Cerro de la Cruz (Hill of the Cross) for panoramic views of the island and Panama City
- Visit the Church of San Pedro, the second-oldest church in the Western Hemisphere
- Explore the village with its colorful houses and connection to French painter Paul Gauguin
- Enjoy fresh seafood at restaurants along the beachfront
Pro Tip: Ferries to Taboga run several times daily from Panama City’s Amador Causeway. The island gets crowded on weekends with day-trippers from the capital. Visit mid-week for a more peaceful experience or book a stay at one of the island’s small hotels to enjoy the quiet evenings.
15. Gamboa, Canal Zone
Located where the Chagres River meets the Panama Canal, Gamboa offers a unique opportunity to experience the canal zone’s natural environment. This former Canal Zone town is now a hub for ecotourism with easy access to wildlife and rainforest experiences.
Boat tours on Gatun Lake offer close encounters with wildlife and views of ships transiting the canal
Why Visit
Gamboa provides a perfect blend of Panama Canal history and rainforest experiences. Its strategic location allows visitors to observe both the engineering marvel of the canal and the rich biodiversity that surrounds it, all within easy reach of Panama City.
Highlights
- Take a boat tour to Monkey Island to see several primate species in their natural habitat
- Visit the Gamboa Rainforest Resort’s aerial tram for canopy-level forest views
- Hike the Pipeline Road, one of the world’s premier bird-watching locations
- Fish for peacock bass and other species in Gatun Lake
- Observe canal operations from a different perspective than the main visitor centers
Pro Tip: Gamboa is just 30 minutes from Panama City but has limited public transportation options. Consider booking tours that include transportation or rent a car. Early morning offers the best wildlife viewing opportunities and cooler temperatures for hiking.
16. Isla Grande, Colón Province
Located off Panama’s Caribbean coast near Portobelo, Isla Grande offers a laid-back island experience with a distinct Afro-Caribbean flavor. This small island is ringed by coral reefs and coconut palms, creating a postcard-perfect tropical setting.
Isla Grande’s palm-fringed beaches offer a quintessential Caribbean experience
Why Visit
Isla Grande provides a more accessible and less expensive alternative to other Caribbean islands in Panama. Its authentic atmosphere, beautiful beaches, and proximity to the mainland make it ideal for travelers seeking Caribbean charm without complex logistics.
Highlights
- Relax on the island’s main beach or discover more secluded coves around the coastline
- Snorkel or dive the coral reefs surrounding the island
- Hike to the historic lighthouse (El Faro) for panoramic views
- Experience local Afro-Caribbean culture through food, music, and community interactions
- Take a boat tour around the island to reach hidden beaches and snorkeling spots
Pro Tip: Isla Grande has no ATMs and most places don’t accept credit cards. Bring sufficient cash for your stay. Cell service is limited, so a reliable eSIM will help you stay connected where possible. The island is busiest during Panamanian holidays, so plan accordingly.
17. Gulf of Chiriquí, Western Panama
The Gulf of Chiriquí on Panama’s Pacific coast encompasses numerous islands, marine protected areas, and coastal communities. This less-visited region offers excellent marine experiences without the crowds of more popular destinations.
The Gulf of Chiriquí contains dozens of uninhabited islands with pristine beaches
Why Visit
The Gulf of Chiriquí offers world-class marine experiences in a less-developed setting. From whale watching to sport fishing to island hopping, the gulf provides numerous activities for nature lovers and those seeking tranquility away from tourist centers.
Highlights
- Explore the islands of Gulf of Chiriquí National Marine Park
- Watch humpback whales during their migration season (July to October)
- Stay at eco-lodges on private islands for an exclusive experience
- Enjoy world-class sport fishing for marlin, tuna, and dorado
- Visit the coastal town of Boca Chica as a gateway to the gulf’s islands
Pro Tip: The Gulf of Chiriquí is best accessed from the town of Boca Chica or from David city. Book accommodations and boat tours in advance as options are limited. The dry season (December to April) offers the best conditions for marine activities.
18. Playa Venao, Azuero Peninsula
Once a hidden surf spot, Playa Venao has developed into one of Panama’s premier beach destinations. This horseshoe-shaped bay on the Azuero Peninsula offers consistent waves, beautiful scenery, and a growing community of international residents and visitors.
Playa Venao’s consistent waves and stunning sunsets have made it a favorite among surfers
Why Visit
Playa Venao combines excellent surfing conditions with a laid-back beach lifestyle. The area has developed rapidly in recent years, adding yoga retreats, eco-lodges, and international restaurants while maintaining its natural beauty and relaxed atmosphere.
Highlights
- Surf at a beach break suitable for all levels, with consistent waves year-round
- Take surfing lessons from one of several surf schools
- Practice yoga at beachfront studios with ocean views
- Enjoy the growing food scene with options ranging from local seafood to international cuisine
- Experience beach parties and live music at bars along the shore
Pro Tip: Playa Venao is remote and public transportation is limited. Consider renting a car in Panama City or arranging a shuttle. The area has better connectivity than many beach destinations in Panama, but a reliable eSIM will ensure you stay connected.
19. Los Cangilones, Chiriquí Province
Los Cangilones is a unique natural swimming hole formed by a river flowing through a narrow canyon of volcanic rock. Located near the town of Gualaca in Chiriquí Province, this hidden gem offers a refreshing natural experience off the typical tourist path.
Los Cangilones offers a unique swimming experience in a natural rock canyon
Why Visit
Los Cangilones provides a distinctive natural attraction that’s popular with locals but still relatively unknown to international visitors. The canyon’s clear, cool waters offer a perfect respite from Panama’s heat, and the surrounding area provides opportunities for picnicking and relaxation.
Highlights
- Swim in the refreshing turquoise waters of the narrow canyon
- Jump from the rocks into deeper sections of the river (for the adventurous)
- Relax on the smooth rock surfaces surrounding the canyon
- Enjoy a picnic in the designated areas near the river
- Experience a local attraction popular with Panamanian families
Pro Tip: Los Cangilones is busiest on weekends and holidays when local families visit. Go on weekdays for a more peaceful experience. The site has basic facilities including changing areas and food vendors, but bring your own supplies if you plan to spend the day.
20. Guna Yala (San Blas Islands), Caribbean Coast
The San Blas Islands deserve a second mention as they offer such diverse experiences across their 365+ islands. Beyond the popular day-trip destinations, the more remote islands provide opportunities for deeper cultural immersion and pristine natural environments.
Visiting traditional Guna villages offers insight into this autonomous indigenous culture
Why Visit
Exploring the less-visited parts of Guna Yala provides a more authentic experience of Guna culture and pristine environments. By venturing beyond the popular islands, travelers can support community-based tourism initiatives and experience the archipelago’s full diversity.
Highlights
- Stay in community-run accommodations on islands like Naranjo Chico or Isla Diablo
- Learn about traditional Guna crafts, including mola textile art
- Participate in sustainable fishing with local guides
- Visit the mainland communities to understand the full context of Guna life
- Experience traditional ceremonies if invited by community members
Pro Tip: For a deeper experience in Guna Yala, consider multi-day tours that visit different islands and mainland communities. Respect local customs and photography restrictions. Book with operators that work directly with Guna communities to ensure your visit benefits local people.
Conclusion: Your Panama Adventure Awaits
Panama offers an extraordinary diversity of experiences in a relatively compact country. From the engineering marvel of the Panama Canal to the pristine beaches of San Blas, from the cool mountain retreats of Boquete to the vibrant culture of the Azuero Peninsula, Panama rewards travelers with unforgettable experiences and warm hospitality.
The best time to visit Panama is during the dry season from December to April, though the country’s varied microclimates mean there’s always somewhere with good weather. Whether you’re seeking adventure, relaxation, cultural experiences, or wildlife encounters, Panama’s diverse destinations deliver memorable experiences for every type of traveler.
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